Pfizer Recalls BP Drugs Because of Potential Carcinogen

Pfizer Recalls BP Drugs Because of Potential Carcinogen

[ad_1] Pfizer is voluntarily recalling some antihypertensive medications because of unacceptable levels of a potential carcinogen, the company announced.  The affected products are quinapril HCI/hydrochlorothiazide (Accuretic) tablets that Pfizer distributes, and two authorized generics, quinapril plus hydrochlorothiazide and quinapril HCI/hydrochlorothiazide, distributed by Greenstone. The drugs have been withdrawn because of the presence of nitrosamine, N-nitroso-quinapril. “Although long-term ingestion of…

Pneumonia Decision Tool Reduces Death in ED Patients

Pneumonia Decision Tool Reduces Death in ED Patients

[ad_1] The use of an electronic clinical decision support tool called “ePNa” reduced severity-adjusted, 30-day, all-cause mortality by 38% across 16 community hospitals in Utah compared with predeployment levels, a 3-year, pragmatic, cluster-controlled study shows. “We designed the ePNa specifically to require minimal input from the clinician so everything it does is already in the electronic…

Surgery Groups Push Back on VARC-3 Valve Trial Definitions

Surgery Groups Push Back on VARC-3 Valve Trial Definitions

[ad_1] Five international cardiac surgery associations have banded together to address “substantive concerns” regarding the recently updated Valve Academic Research Consortium 3 (VARC-3) clinical endpoint definitions for aortic valve research. The VARC-3 update was a multidisciplinary effort that included more than a dozen new or modified definitions for use in transcatheter and surgical aortic valve…

A Novel Tool for Assessing Breast Cancer Risk

A Novel Tool for Assessing Breast Cancer Risk

[ad_1] Using MammoRisk, a software tool used to estimate an individual’s 5-year risk of developing breast cancer, is feasible in community practices, according to a recent study. The assessment is based on a patient’s clinical data and breast density, with or without a polygenic risk score (PRS). Adding the latter criterion to the model led to…

Shift Work May Affect Timing of Menopause Onset

Shift Work May Affect Timing of Menopause Onset

[ad_1] Exposure to shift work appears to influence the timing of menopause onset in both directions, new data suggest. Among nearly 4000 Canadian women surveyed, one in five reported exposure to shift work — that is, outside of the usual daytime business hours — at some point in their lives. After adjustment for confounders, rotating…